Vander Griend Lab Via:

Vander Griend Lab

  1. Chen JL, et al. Deregulation of a Hox Protein Regulatory Network Spanning Prostate Cancer Initiation and Progression. Clinical Cancer Research; 2012. URL
  2. Reyes EW, et al. Growth Kinetics of CD133-Positive Prostate Cancer Cells. The Prostate; 2013. URL
  3. Kregel S, et al. Sox2 is an Androgen Receptor-Repressed Gene that Promotes Castration-Resistant Prostate Cancer. PLoS ONE; 2013. URL / METRICS
  4. Cai Y, et al. Formation of Human Prostate Epithelium Using Tissue Recombination of Rodent Urogenital Sinus Mesenchyme and Human Stem Cells. The Journal of Visualized Experiments (JoVE); 2013. URL
  5. Kregel S, et al. The Pluripotency Factor Nanog is Directly Upregulated by the Androgen Receptor in Prostate Cancer Cells. The Prostate; 2014. URL
  6. Reyes EE, et al. Quantitative characterization of androgen receptor protein expression and cellular localization in circulating tumor cells from patients with metastatic castration-resistant prostate cancer. Journal of Translational Medicine; 2014. URL
  7. Reyes EE, et al. Molecular Analysis of CD133-Positive Circulating Tumor Cells from Patients with Metastatic Castration-Resistant Prostate Cancer. Journal of Translational Science; 2015. URL
  8. Kregel S, et al. Acquired Resistance to the Second-Generation Androgen Receptor Antagonist Enzalutamide in Castration-Resistant Prostate Cancer. OncoTarget; 2016. URL
  9. Nottingham CU, et al. SOX2 Expression in Patients who Underwent Radical Cystectomy for Urothelial Carcinoma of the Bladder. Clinics in Oncology; 2016. URL
  10. Brechka H, et al. Contribution of Caudal Müllerian Duct Mesenchyme to Prostate Development. Stem Cells and Development; 2016. URL
  11. Brechka H, et al. HOXB13 Mutations and Binding Partners in Prostate Development and Cancer: Function, Clinical Significance, and Future Directions. Invited and Peer-Reviewed Review Article. Genes and Diseases; 2017. URL
  12. McAuley E, et al. Magnetic Resonance Imaging and Molecular Characterization of a Hormone-Mediated Murine Model of Prostate Enlargement and Bladder Outlet Obstruction. American Journal of Pathology; 2017. URL
  13. Bhanvadia R, et al. MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease. Clinical Cancer Research; 2018. URL
  14. McAuley E, et al. Sox2 Expression Marks Castration‐Resistant Progenitor Cells in the Adult Murine Prostate. Stem Cells; 2019. URL

Collaborative Work

  1. Isikbay M, et al. Glucocorticoid receptor activity contributes to resistance to androgen-targeted therapy in prostate cancer. Hormones and Cancer; 2014. URL
  2. Leventhal DS, et al. Dendritic cells coordinate the development and homeostasis of organ-specific regulatory T cells. Immunity; 2016. URL
  3. Kach J*, et al. Selective glucocorticoid receptor modulators (SGRMs) delay castrate-resistant prostate cancer growth. Molecular Cancer Therapeutics; 2017. URL
  4. Urbanucci A, et al. Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer. Cell Reports; 2017. URL
  5. House L,et al. Metabolism of Megastrol Acetate in Vitro and the Role of Oxidative Metabolites. Xenobiotica; 2017. URL
  6. Gillard M, et al. Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer. European Urology Focus; 2017. URL
  7. Giri VN, et al. Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017. Journal of Clinical Oncology; 2018. URL
  8. VanderWeele DJ, et al. Genetic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy. European Urology Focus; 2017. URL
  9. Peak TC, et al. Exosomes secreted by placental stem cells selectively inhibit growth of aggressive prostate cancer cells. Biophys Res Communications; 2018. URL
  10. Gillard M, et al. Elevation of stromal-derived mediators of inflammation promote prostate cancer progression in African American men. Cancer Research; 2018. URL
  11. Hainline KM, et al. Self-Assembling Peptide Gels for 3D Prostate Cancer Spheroid Culture. Macromolecular Bioscience; 2018. URL

Post-Doctoral Fellowship

  1. Vander Griend DJ, et al. Conversion of Androgen Receptor Signaling From a Growth Suppressor in Normal Prostate Epithelial Cells to an Oncogene in Prostate Cancer Cells Involves a Gain of Function in c-Myc Regulation. International Journal of Biological Sciences; 2014. URL
  2. Litvinov IV and Vander Griend DJ, et al. PC3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor. The Prostate; 2006. URL
  3. Litvinov IV, Vander Griend DJ, et al. Low Calcium-Serum Free Defined Media Selects For Growth of Normal Prostatic Epithelial Stem Cells. Cancer Research; 2006. URL
  4. Litvinov IV, Vander Griend DJ, et al. Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells. PNAS; 2006. URL
  5. Vander Griend DJ, et al. Stabilizing Androgen Receptor in Mitosis Inhibits Prostate Cancer Proliferation. Cell Cycle; 2007. URL
  6. Vander Griend DJ, et al. The Role of CD133 in Normal Human Prostate Stem Cells and Malignant Cancer Initiating Cells. Cancer Research; 2009. URL
  7. Vander Griend DJ, et al. Amino-acid Containing Thapsigargin Analogs Deplete Androgen Receptor Protein via Synthesis Inhibition and Induce the Death of Prostate Cancer Cells. Molecular Cancer Therapeutics; 2009. URL
  8. Vander Griend DJ, et al. Dual-Label Centromere and Telomere FISH Identifies Human, Rat, and Mouse Cell Contribution to Multispecies Recombinant Urogenital Sinus Xenografts. The Prostate; 2009. URL
  9. Vander Griend DJ, et al. Cell-Autonomous Intracellular Androgen Receptor Signaling Drives the Growth of Human Prostate Cancer Initiating Cells. The Prostate; 2010. URL
  10. D’Antonio JM*, Vander Griend DJ*, et al. Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling. PLoS One; 2010. URL

Graduate School

  1. Kim HL*, Vander Griend DJ*, et al. Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers. Cancer Research; 2001. URL
  2. Yamada SD, et al. Expression of Mitogen-activated Protein Kinase Kinase 4 (MKK4), a Metastasis Suppressor Gene, is Downregulated in Human Ovarian Carcinomas. Cancer Research; 2002. URL
  3. Vander Griend DJ, et al. The Context-Dependent Activation of the JNK Kinases JNKK1/MKK4 and MKK7 Suppresses Metastatic Colonization. Cancer Research; 2005. URL
  4. Hickson JA, et al. The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma. Cancer Research; 2006. URL